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Co-Authors and Peer Reviewers
Arna Meyer
Data Interoperability and Standardization
Thomas Terronez
Technology Infrastructure and Access

Dr. Tarek Aly
Provider and Patient Rights

Dr. Matta
Clinical Quality and Efficacy

Dr. Eric Roman
Change Management and Enablement

Dr. Aman Kaur
Workforce Implications

Holly Mitchell
Patient Experience and Patient Rights
About Oral Health United
Oral Health United is a pioneering for-benefit corporation created by its community of changemakers dedicated to transforming oral healthcare through ethical innovation. Unlike traditional healthcare entities, our collaborative model empowers diverse stakeholders—including providers, patients, technologists, and community advocates—to collectively drive system-wide change.
Future Of Dentistry Living Document Approach
This whitepaper is designed as a living document that evolves alongside the rapidly changing innovation landscape. As new technologies emerge, implementation strategies develop, and our understanding deepens, we will continuously update this resource with fresh insights, case studies, and guidance. Additional complementary resources will be connected to this document over time, creating an expanding knowledge ecosystem that helps our community make sense of emerging futures in oral healthcare. We invite ongoing contribution and discussion as we collectively navigate this transformation.
Our Mission
Our mission centers on three core pillars:
Access
Democratizing oral healthcare by removing financial, geographic, and systemic barriers that prevent millions from receiving essential dental services
Quality
Advancing evidence-based, patient-centered care models that prioritize prevention and comprehensive health outcomes
Wellbeing
Recognizing the integral connection between oral health and overall wellbeing, fostering integrated approaches that address the whole person

Dental Practices and DSOs that strategically integrate human expertise with intelligent agent technologies will deliver superior patient and provider experiences, drive higher treatment acceptance rates, and elevate clinical outcomes—creating a new standard of comprehensive care.
In today's rapidly evolving technological landscape, intelligent agents are emerging as transformative tools redefining patient care and practice management across the dental industry. What began as basic digital tools for scheduling and record-keeping has evolved into sophisticated systems capable of autonomous decision-making in diagnosis, treatment planning, and practice operations.
This evolution marks a pivotal shift, positioning intelligent agents as active participants in dental practices, dental service organizations (DSOs), insurance processing, and clinical education. From automated radiograph analysis to predictive maintenance for equipment and personalized patient communication systems, these technologies are revolutionizing every aspect of dental service delivery.
The advancement of intelligent agents in dentistry offers unprecedented opportunities for improving clinical outcomes and practice efficiency. Their ability to process vast amounts of patient data, identify subtle patterns in radiographs, and manage complex administrative tasks with minimal human intervention promises significantly enhanced diagnostic accuracy and streamlined workflows. However, as dental practices embrace these technologies, it is essential to address challenges related to implementation costs, staff training, data security, and maintaining the human touch that patients value.
While adoption accelerates across the dental sector, ensuring these technologies align with clinical best practices and patient-centered care remains paramount. The goal is to augment the clinical judgment of dental professionals—not replace it—creating a synergy that elevates the standard of care while improving practice profitability.
This whitepaper serves as a crucial resource for dental practitioners, DSO executives, and industry stakeholders involved in shaping the future of oral healthcare. By exploring the capabilities and implications of intelligent agents in dentistry, professionals can better understand how to leverage these systems to enhance clinical decision-making, improve patient experiences, and drive practice growth.
With thoughtful implementation and ongoing evaluation, intelligent agents can become invaluable allies in advancing dental care, reducing provider burnout, and improving oral health outcomes across diverse patient populations.

Dental Practices and DSOs that strategically integrate human expertise with intelligent agent technologies will deliver superior patient and provider experiences, drive higher treatment acceptance rates, and elevate clinical outcomes—creating a new standard of comprehensive care.
This paper examines the development and functionality of intelligent agents in dentistry – and the implications of their use – amid rapid advances in large language and multimodal models. Defined as autonomous systems that sense and act upon the oral healthcare environment to achieve clinical and operational goals, these agents are being deployed across dental practices, DSOs, laboratories, and insurance networks.
This transformation requires the adaptation of governance frameworks to ensure responsible adoption within the unique context of oral healthcare.
Dental intelligent agents, comprising components such as diagnostic sensors, clinical decision support systems, and practice management tools, have evolved from rule-based scheduling systems to advanced models capable of complex treatment planning and independent operation.
Enabled by breakthroughs in deep learning, reinforcement learning and the transformer architecture, these agents span applications from radiographic analysis to personalized patient engagement. This progression now encompasses more sophisticated utility-based agents that incorporate patient history, treatment outcome prediction, and integration with dental-specific tools, broadening their capabilities across preventive, restorative, and specialty care.
Benefits
Productivity Gains
Intelligent agents provide significant productivity gains for understaffed dental practices.
Specialized Diagnostic Support
Enhanced diagnostic capabilities for complex cases through advanced imaging analysis.
Operational Efficiency
Improved efficiency in insurance verification, claims processing, and inventory management.
Risks
Clinical Protocol Misalignment
Potential misalignment with established clinical protocols.
Ethical Concerns
Transparency and accountability challenges in patient care decisions.
Data Security
Concerns about patient data protection and privacy.
Future advances in dental intelligent systems are likely to involve multi-agent systems (MAS), where agents collaborate to address complex challenges such as comprehensive treatment planning across specialties and predictive oral health monitoring. More advanced systems introduce new demands for interoperability with existing practice management software and communication standards to function effectively within dental workflows, while these protocols still need to be debated and agreed upon by professional dental organizations and regulatory bodies.
This paper highlights the need for robust governance, ethical guidelines, and a cross-sectoral consensus to integrate intelligent agents safely into dental education, clinical practice, and business operations. As more advanced dental agents continue to proliferate, it is imperative that their transformative potential for improving oral health outcomes remains balanced with essential patient safety, data security, and professional governance considerations unique to dentistry.

Intelligent agents are becoming more sophisticated within the dental industry, with significant implications for clinical decision-making, practice accountability, and regulatory oversight. As artificial intelligence continues to integrate into various facets of oral healthcare, understanding the role of these agents, their capabilities, and likely impact is crucial for dental practitioners, DSO executives, dental educators, and other stakeholders involved in shaping the future of dentistry.
The concept of an agent in dentistry – an entity that perceives the clinical and operational environment through sensors and acts on it through digital interfaces – has been constantly evolving since the beginning of practice management automation. With recent advances in large language models (LLM) and large multimodal models (LMM) that can process clinical notes, radiographs, intraoral scans, and patient communications, intelligent dental agents are moving into a new phase of rapid development and clinical application.
Early Adoption
Basic Digital Tools
Initial implementation of scheduling and record-keeping systems in dental practices.
Evolution
Practice Management Automation
Development of more sophisticated practice management systems with basic automation capabilities.
Current State
Intelligent Agents
Emergence of diagnostic assistants, predictive models, and automated systems throughout the dental care ecosystem.
Near Future
Autonomous Systems
Progression toward innovative systems with increased autonomy, capable of completing clinical and administrative tasks with minimal human involvement.
As dental intelligent agents continue to advance, the profession is gradually progressing towards innovative systems with increased autonomy, capable of completing clinical and administrative tasks with minimal involvement from the dental team. This heralds a new era of technology-driven efficiency with the potential to affect every aspect of oral healthcare delivery – from solo practices to large DSOs, dental laboratories, insurance companies, and dental schools.
Given these far-reaching implications, it is crucial to consider patient safety, data security, and governance measures specific to dentistry to guide the responsible development and implementation of advanced dental agents. The integration of these technologies must align with the profession's commitment to evidence-based care and ethical practice while addressing dental-specific challenges such as treatment plan variability and the highly personalized nature of oral healthcare.
This paper first defines intelligent agents in the dental context before outlining different types of agents and their evolution within practice settings. The final section looks ahead to summarize emerging technical and socioeconomic implications of deploying intelligent agents in dentistry – along with possible measures to mitigate risks while maximizing benefits for practitioners, DSOs, and the patients they serve.

What is a Dental AI Agent?
In today's rapidly evolving dental technology landscape, AI is no longer just a buzzword—it's becoming an essential part of the modern practice. But what exactly is a dental AI agent?

"A dental AI agent responds autonomously to inputs from the practice's digital infrastructure to make complex decisions that enhance clinical outcomes, operational efficiency, and patient experiences."
Dental AI agents operate with both autonomy (functioning independently across system boundaries) and authority (accessing and modifying data within defined parameters) to optimize the dental care environment.
A dental agent comprises several interconnected components that work together to transform practice operations:
User Input
The interactions from dental professionals, staff, and patients that the AI processes—including clinical findings, treatment plans, scheduling requests, and insurance information.
Dental Practice Environment
The comprehensive digital ecosystem where the agent operates, consisting of three essential systems:
Sensors & Percepts
The mechanisms through which the agent perceives the practice environment—integrations with clinical data, practice metrics, and patient information that inform the agent's understanding.
Control Centre
The intelligent core that processes information from all practice systems, making decisions and coordinating actions using specialized dental algorithms and models.
Effectors & Actions
The mechanisms through which the agent implements changes across practice systems—from scheduling optimizations to treatment plan sequencing and insurance verification automation.

The development of dental AI agents represents a transformative journey spanning decades:
1980s-1990s
The Digital Revolution Begins
Early dental software began as simple digital replacements for paper records and schedules—essentially digital filing cabinets with rigid workflows and limited capabilities.
2000s
The Rise of Machine Learning
A significant turning point as systems began to learn from aggregated clinical data, adapt over time, and improve performance in areas such as radiographic caries detection and periodontal risk assessment.
2017 Onward
Language Models Transform Capabilities
The rise of Large Language Models revolutionized dental AI capabilities in clinical documentation, patient communication, and treatment planning—producing human-like documentation and engaging in complex communication tasks.
1980s-1990s
Continuous Learning Through Feedback
Modern dental AI agents use various learning techniques, including reinforcement learning with feedback from dental professionals, allowing them to continuously refine their abilities and adapt to practice-specific patterns.

Over the past decade, several technological advancements have dramatically expanded the capabilities of dental AI:
Large Dental Models
What they are: Language and multimodal models specifically trained on dental datasets
Why they matter: They can process multiple inputs simultaneously—radiographs, intraoral photos, 3D scans, patient histories, and clinical notes
The transformer architecture has enabled a deeper understanding of the relationships between clinical findings, treatments, and outcomes.
Machine Learning Techniques in Dentistry
Supervised Learning
● Learns from labeled datasets of dental radiographs and clinical outcomes.
● Example: Predicting caries from radiographs.
Reinforcement Learning
● Enables scheduling agents to learn optimal appointment sequencing.
● Example: Adapting to appointment durations and cancellation patterns.
Transfer Learning
● Adapts pre-trained models to dental-specific problems.
● Example: Adapting to unique patient demographics.

Dental AI agents can be categorized based on their capabilities, complexity, and decision-making processes:
Deterministic Dental AI Agents
● Rule-based with fixed clinical protocols
● Predictable behavior with consistent outcomes
● Limited adaptability to new clinical evidence
Non-deterministic Dental AI Agents
● Data-driven and probabilistic
● Flexible and adaptive to new evidence
● Complex decision-making with nuanced recommendations
The Agent Spectrum: From Simple to Advanced
Simple Reflex Agents
Operate based on immediate perception without considering history.
● Automated appointment reminders
● Basic insurance verification tools
● Digital charting alerts
Model-based Reflex Agents
Track parts of the environment not immediately visible.
● Digital shade matching systems
● Maintenance tracking systems
● Equipment monitoring systems
Goal-based Dental Agents
Consider future treatment outcomes in planning.
● Treatment sequencing systems
● Production optimization agents
● Patient communication systems
Utility-based Dental Agents
Employ weighted scoring for optimal decisions.
● Comprehensive treatment planning systems
● DSO resource allocation systems
● Diagnostic assistants with probability scores

Modern dental AI agents feature sophisticated architectures often linked to Large Language Models, with several key components working together:
How Information Flows Through the System
User Input: Dental professionals provide commands (analyze a radiograph, optimize schedule, etc.)
Control Center: Directs input to the appropriate model and orchestrates information flow
Model Processing: The core algorithms (LLMs fine-tuned for dental applications) process the data
Decision-making: Chain-of-thought reasoning enables transparent clinical conclusions
Patient History Integration: Ensures continuity of care through historical context
Specialized Tool Access: Connects to insurance verification, scheduling, and lab systems
Action Implementation: Executes decisions through practice management systems

"The control center acts as the orchestration layer, directing inputs to the model and routing the output to appropriate dental tools or effectors."
Learning Component
The system continuously improves performance as it gathers more practice-specific data and clinical outcomes, adapting to unique patterns of individual practices, provider preferences, and patient demographics.

A dental AI agent system integrates multiple specialized AI agents within a practice or DSO environment, with each agent focused on specific dental workflows while sharing patient and practice data.
System Designs
Mixture-of-agents: Sequential calling of specialized agents (diagnostic → treatment planning → patient communication)
Central orchestration: Coordination between clinical, administrative, and patient engagement agents
Real-World Example: Comprehensive Dental Care Delivery System
How It Works in Practice
A patient arrives at a dental practice equipped with an integrated AI agent system. Each specialized agent handles different aspects of the patient journey:
Diagnostic Agent
Continuously analyzes radiographs, intraoral scans, and clinical photographs.
Treatment Planning Agent
Calculates optimal procedure sequencing based on clinical urgency, insurance coverage, and patient preferences.
Financial Agent
Handles insurance verification, pre-authorizations, and payment arrangements.
Scheduling Agent
Processes appointment requests and adjusts provider schedules based on procedure duration and staff availability.
All agents work together in a coordinated manner to ensure comprehensive care delivery that prioritizes both oral health outcomes and practice productivity.

The future of dental AI lies in multi-agent systems (MAS)—multiple independent AI agents and systems that collaborate, compete, or negotiate across the entire dental ecosystem.
Why Multi-Agent Systems Matter
● Enable parallel task performance across organizational boundaries
● Adapt to changes in complex patient care environments
● Integrate expertise from various dental specialties
Architectural Approaches
Network Architecture
All dental agents communicate with one another to reach consensus on collaborative care objectives.
Example: Coordination between a general dentist, oral surgeon, and dental laboratory for complex implant cases
Supervised Architecture
A "supervisor" agent coordinates interactions when goals diverge and consensus may be unattainable.
Example: Mediating between treatment planning and insurance verification agents to find the best care within coverage limitations
All agents work together in a coordinated manner to ensure comprehensive care delivery that prioritizes both oral health outcomes and practice productivity.
Benefits of Dental MAS
● Reduced care fragmentation: Seamless information flow between providers
● Increased resilience: Systems adapt when provider availability changes
● Expanded expertise: Access to specialty knowledge across the care network
● Scalability: Agents can be dynamically added as practices join networks

" Dental multi-agent systems promise to transform dentistry from a collection of isolated practices to an integrated ecosystem where information flows seamlessly to benefit both providers and patients."

Before integrating dental AI into your practice, consider these key factors:
Technical Requirements
● Integration capabilities with existing practice management systems
● Data security and HIPAA compliance measures
● Hardware specifications for optimal performance
Staff Training
● Role-specific training for clinical team members
● Administrative staff workflow adjustments
● Ongoing education as capabilities evolve
ROI Expectations
● Typical efficiency gains in the first 3-6 months
● Patient experience improvements
● Long-term clinical outcome enhancements

The dental AI revolution is just beginning. As these technologies continue to evolve, practices that embrace them thoughtfully will be positioned to deliver superior patient care while operating more efficiently.
The future dental practice will leverage AI not to replace the human touch that's essential to dentistry, but to enhance clinical decision-making, streamline operations, and create more personalized patient experiences.
Want to Learn More?
This article is based on extensive research into current dental AI technologies and practices. While efforts have been made to ensure accuracy, the field continues to evolve rapidly.